Da pocnem prvu!

Vaša iskustva, pitanja u vezi sa terapijom antagonistima (naltrexon, naloxon) - Nemexin, ReVia, Nalorex.... Postavljajte pitanja i svojim iskustvima pomozite drugima koji se nalaze u sličnoj situaciji.

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Mark_Renton
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Ako ne odgovorite, zvacu Drajzerovu!

Post by Mark_Renton » Wed Aug 24, 2005 11:55 pm

Da, iskombinovacu nalorex+subutex i uraditi se kao nikad u zivotu!!!

Ono sto me zanima (opet moram konkretniji da budem, jer me odgovori ne zadovoljavaju).

Subutex deluje kao agonist na mu-opioid receptore i kao antagonist na kappa-opioid receptore. Sto znaci, da ako nalorex blokira samo kappa-opioid receptore, a subutex deluje na mu receptore - eto zaobilaznog puta do "rada".

DA LI BI (AKO SAM NA NALOREXU) OSETIO "RAD" KAD BIH UZEO SUBUTEX?
Posto subutex "radi" kad se uzme a cist si.
When Hell is full, the dead will walk the Earth.

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Luna
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Post by Luna » Thu Aug 25, 2005 1:25 pm

ne kombinuju nalorex MARK nego naloxon sa subutexom i dobiju suboxone...koji se ovdje daje vise nego subutex sam od sebe zbog zlouporebe...naloxon nema dejstvo nikakvo ako ga uzmes pod jezik dok nalorex ima...
zaboga milog idi na google i ukucaj subutex and suboxone info...ili burenophrine and therapy. Nalorex ili kako ovdje kazu naltrexon nije isto sto i naloxon koji koriste...ovdje u USA-mozda je na balkanu drugacije jer su ljudi otporniji :roll: -je strogo zabranjeno apotekarima da daju nalorex ljudima koji su jos uvijek na terapiji-sve i da ga neces odmah uzeti ne smiju ti zakonom dati zbog DANGEROUS AND POSSIBLY FATAL INTERACTION OF THE TWO.
subutex-je cisti burenophrine-suboxone-burenophrine i naloxon zajedno-novi lijek...je mnogo vise koristen zbog zloupotrebe
nije nauka neka idi na net pa vidi i sam sta pisu neki od najpoznatijih doktora svijeta koji se bave s tim..pa ako ja ne znam jebi ga valjda oni znaju
ma jarane nerviras me ba...niko nije glup da ne vidi sta ti radis...kome je toliko hitno da uzme nalorex ako je na subutexu ha? nikome...zasto bi se neko zurio za to? ali ako je neko na nalorexu i zeli da uzme subutex to je vec logicnije da neko zeli odmah da uzme...uzmi jarane...javi kako je bilo...nadam se da ce ti to biti lekcija za svagda.
I ne moze se gudrurati subutexom..nije dovoljno jak i ne prekriva cijeli opiat receptor kao dop pa se zato lakse skinuti s njega i ne stvara toleranciju kao dop.
ja sam proucila i naucila jako puno o subutexu-sto sama sto sa doktorom specialistom poznatim u americi po svojim istragama i uspijesnim terapijama subutexom i suboxonom.pa jebi ga bice da ni on ne zna sta prica
ma necu ti vise nista ni reci kad ne zelis moje misljenje-nego eto ja guska zao mi da se tip sjebe ko foka i zavrsi u hitnoj...ma boli me...uzmi 2subutexa i 3nalorexa mozda te bolje pukne....dodaj i malo dopa pa kad je bal nek' je maskembal :roll:

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Luna
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clonidine & opiate treatment

Post by Luna » Thu Aug 25, 2005 3:22 pm

OPIATE TREATMENT
Inpatient and outpatient clinical studies have shown that clonidine is a reasonably safe, specific, and effective agent for detoxifying opiate addicts. Clonidine seems best suited for use as a transitional treatment between opiate dependence and induction onto the opiate antagonist naltrexone. Dosage regimens of clonidine must be individualized according to symptoms and side effects and closely supervised because of varying sensitivity to clonidine's sedative, hypotensive, and withdrawal-suppressing effects. Clonidine is an important new treatment option for selected opiate addicts and may be the treatment of choice when detoxification using methadone is inappropriate, unsuccessful, or unavailable. Lofexidine, a structural analogue of clonidine, may be safer and more effective as an opiate detoxification treatment. It has similar withdrawal-suppressing actions but causes little hypotension and sedation. Although clonidine and lofexidine may be highly effective in helping opiate addicts achieve initial abstinence, a multi-modality aftercare treatment approach including naltrexone and psychotherapy may be necessary to maintain an abstinent state.
History
How It Works

Clonidine is a blood pressure medication that relaxes the smooth muscle of blood vessels, causing them to widen, or dilate. This reduces the pressure of blood flow through the artery. Clonidine's effect on hot flashes is not well understood.

(back to top)
Why It Is Used

Clonidine can be used to treat hot flashes. Because it is a nonhormonal treatment, women with a history of breast cancer can use it without increasing the risk of further cancerous cell growth (as in the case of estrogen treatment).

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Mark_Renton
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Luna, razumem ja tebe

Post by Mark_Renton » Thu Aug 25, 2005 5:06 pm

Luna, nemoj me pogresno shvatiti, razumem ja da naloxon i nalorex nije isto, juce sam procitao 35 PDF fajlova o subutexu i suboxon-u i znam razliku!!!
Ne zanima mene suboxon posto ga NEMAM!
Vedad mi je konkretno odgovorio na pitanje: AKO PREKO NALOREXA UZMEM SUBUTEX, NECU SE URADITI.
When Hell is full, the dead will walk the Earth.

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Mark_Renton
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haha

Post by Mark_Renton » Tue Aug 30, 2005 12:46 am

I'm looking forward to it already.
When Hell is full, the dead will walk the Earth.

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Mark_Renton
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Post by Mark_Renton » Wed Aug 31, 2005 4:34 pm

Dobio sam zvanicni odgovor iz Drajzerove:

nalorex blokira i kappa i mu receptore. subutex deluje kao agonist na mu receptore koji su blokirani nalorexom, tako da nema dejstva... smrc

Nego vedade, hoces li ti podeliti tu tajnu lakog zaobilazenja? Ja svaki dan dolazim i gledam... al' nista. Moze i na private.
When Hell is full, the dead will walk the Earth.

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Luna
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Post by Luna » Fri Sep 02, 2005 2:37 pm

Naloxone

Life-saving drug sold over the counter, does not produce side effects when injected in persons that are not taking opiates. In Suboxone (subutex+naloxone) it has no effects unless injected (creates significant withdrawal symptoms)

Naltrexone

A drug that was synthesized by Blumberg in 1965; it is a competitive agonist of the opiate receptors and progressively inhibits sensitivity to opiates. It was commercialized in 1987 when it was successively used for treating drug addiction relapses and as part of detoxification programs based on substitute and/or symptomatic drugs. It can cause violent withdrawal effects in persons addicted to narcotic drugs and therefore protocols using naltrexone must only be used 7-10 days after the drug addict has abstained from using opiates. It has proved to be a valid alternative in treatment based on agonists for patients that are motivated to stop using opiates and agonists on a daily basis. It is also reduces alcohol craving. Commercial names: Antaxone; Nalorex.

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LEJLA
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Post by LEJLA » Fri Nov 25, 2005 11:29 pm

Može neko da mi kaže kako se dolazi do Subotexa ili nečeg drugog za skidanje sa dopa ,jer nemam predstavu kako se nabavlja!Stim da sam iz Beograda i ovde ga nema. Raspitivala sam se za skidanje ali mi neki kažu da nabavim matadon!Kad sam pročitala o čemu svi vi pričate sad mi je lakše !A navučena sam već 2 god "konstantno" i opasno sam otišla u aut!ŠTA DA RADIM LJUDI !KAKO DA GA NABAVIM ! (BAREM DA NAPRAVIM MALU PAUZU AKO ME RAZUMETE)!MOŽE LI TO NEŠTO NA CRNO ,DA NIKO NEMORA DA ZNA ! :(

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Luna
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Post by Luna » Sat Nov 26, 2005 10:35 am

lejla.....
jebi ga sta da ti kazem.....javi se na pm ok??? Metadon je temporary solucija....tj moze to i da potraje godinammaaa...no problem i dalje nije rijesen. AKo ti je to jedini izlaz..onda ok. idi uzimaj 15 dana. I ne vishe. I bices ok. fizicki. A za psihu...e to je druga prica skroz. eto javi mi se....ne odustaj. Napravila si veliki korak sada jel znash to??? Priznala si da imash problem i zelis da ga rijesis....to je veliko. Ponosna sam na tebe. Ne znam te...ali te znam.. ! Tu si...neka te tu s nama ok?
pisi i pisi i pisi.....samo polako. Smanji uzimanje ...na minimum ga svedi...to je prvo...ajde...pricacemo uskoro.
cmok i puno srece

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Vlado_M
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Post by Vlado_M » Sat Nov 26, 2005 12:29 pm

Kako me nerviraju tipovi u tripu da se narkomanija moze sakriti od javnosti i to... Ne moze Lejla nista tajno. Svi ce te provaliti, prije ili kasnije, i ti ces morati traziti pomoc (i neces imati vremena da razmisljas o tome da li se ofiras ili ne, ili ti nece biti vazno).

Bolje da je trazis prije, nego kasnije (jesam mudar, jebote). Inace, znam da ovi iz klinike La Vita u Lukavici subotex narucuju iz Bgd.

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